Blood vessels are the body’s essential architecture that exists in order to nurture cells with sufficient nutrients and oxygen. Angiogenesis, or the formation of new blood vessels, is of great ...

Angiogenesis is a complex morphogenetic process whereby endothelial cells from existing vessels invade as multicellular sprouts to form new vessels. Here, we have engineered a unique organotypic model ...

Angiogenesis is crucial during many physiological processes and is influenced by various biochemical and biomechanical factors. Models have proved useful in understanding the mechanisms of ...

To provide sufficient oxygen to tissues and organs within the body, blood vessels need to sprout new offshoots to form a widespread blood supply network, much like the trunk, branches, and twigs of a ...

Researchers at the Institute of Industrial Science (IIS), the University of Tokyo, CNRS and INSERM, report a new organ-on-a-chip technology for the study of blood vessel formation and drugs targeting ...

Blood vessels are the roads and highways of the cardiovascular system, carrying oxygenated blood cells, nutrients, and immune cells in and out of the heart, brain, and other various organs in the body ...

What is "normal" blood vessel growth? The branching network of blood vessels in our bodies is vast. Lined up end-to-end, the blood vessels in just one adult could encircle the Earth twice. While it's ...

For months, Sabrina Staples stared at a silicone chip no bigger than a postage stamp, trying to coax cells into doing something remarkable. But every time she loaded her delicate microfluidic device ...

Extensive sprouting of endothelial cells (green) seen in engineered pseudo-islets also containing β-cells (red) after five days; cell nuclei are shown in blue. Type 1 diabetes results in the ...

'Merlin' serves as a gatekeeper in new blood vessel formation. Merlin suppresses internalization of VEGFR2, which is important for the formation of 'tip' endothelial cells. Blood vessels are the ...