By recreating a fetal liver niche, FLOs show how liver and immune cells co-develop. Learn more about new groundbreaking ...

Researchers successfully implanted a genetically modified pig liver into a human, proving that such an organ can function for an extended period. The graft supported essential liver processes before ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have ...

Scientists identify measurable cellular changes that flag higher cancer risk more than a decade before tumors appear. In ...

A modified pig liver transplanted into a human patient appears to have functioned normally for the duration of the investigation with no signs of rejection. For 10 days, the liver performed its basic ...

Scientists from Uppsala University and several other research institutions have created a personalized human liver model that can significantly improve the diagnosis and treatment of diseases such as ...

A multidisciplinary team from China has successfully transplanted a gene-modified pig liver into a human recipient diagnosed with brain death. During a 10-day observation period, the porcine liver ...

Microfluidic chips that mimic human livers are better at predicting whether a drug is toxic to the liver than conventional animal models used in preclinical experimentations, claims a new study from ...

Scientists have developed a functional human hepatic tissue in a mouse host. The human hepatic tissue, in the mice, is composed of human hepatocytes and non-parenchymal cells (NPCs) including human ...

This article is based on a poster originally authored by L. Fäs, F. Wenz, M. Tu, K. Sanchez, N. Zapiórkowska-Blumer, H. Varga and K. Kaczmarska, which was presented at ELRIG Drug Discovery 2024 in ...