Inflammation is a crucial part of the body's defense mechanism, playing a key role in fighting infections and repairing tissue damage. Basophils, a type of immune cell that makes up less than 1% of ...

A new study shows that thymic stromal lymphopoietin (TSLP, a cytokine that promotes allergic inflammation) and basophils contribute to the pathogenesis of eosinophilic oesophagitis (EoE). These ...

In experiments with ARDS model mice, researchers from Japan found that basophils, a type of white blood cells, release interleukin-4, a signaling molecule that suppresses inflammatory neutrophils ...

A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research ...

Researchers from Tokyo Medical and Dental University (TMDU) find that pre-basophil and mast cell progenitors differentiate into pre-basophils before producing mature basophils in mice Tokyo, Japan – ...

Big changes often happen in small steps, and it’s not always easy to see how we get from point A to point B. Now, researchers from Japan have found a new step in the process of cell differentiation ...

C. Ohnmacht et al., “Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths,” Immunity, 33:364-74, 2010. Free F1000 Evaluation Basophils were deemed critical in ...

Basophils are the rarest type of white blood cell (WBC). Sometimes called granulocytes, the cells hold tiny granules full of histamine. Basophils can also trigger your allergic reaction. They can ...

Basophils are white blood cells that the bone marrow makes. They play a role in a healthy immune system. Having more or less basophils than usual may be a sign of inflammation, hyperthyroidism, or ...